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Next oral administration of radiolabeled zafirlukast to volunteers, urinary excretion accounts for roughly 10% of the dose and the rest is excreted in feces. Zafirlukast is just not detected in urine.Zafirlukast is extensively hepatically metabolized by an enzyme identified as CYP2C9. Zafirlukast inhibits the action of CYP3A4, bringing about drug-d